Find Cheap Panama Canal Cruises in May 2026

Starts: Sun, Apr 12, 2026 from Mobile

Ends: Tue, Apr 28, 2026 in Seattle

Cruise Ports: Mobile, Cartagena, Cruising the Panama Canal, Puntarenas, Cabo San Lucas, Seattle

Starts: Sat, Apr 11, 2026 from Tampa

Ends: Mon, Apr 27, 2026 in Seattle

Cruise Ports: Tampa, Georgetown , Cartagena, Cruising the Panama Canal, Puntarenas, Cabo San Lucas, Seattle

Starts: Thu, Apr 23, 2026 from Miami

Ends: Mon, May 11, 2026 in Seattle

Cruise Ports: Miami, Cartagena, Colon, Cruising the Panama Canal, Puntarenas, Cabo San Lucas, San Diego, Los Angeles, Seattle

Starts: Tue, Apr 14, 2026 from Miami

Ends: Mon, May 4, 2026 in Seattle

Cruise Ports: Miami, Cartagena, Colon, Cruising the Panama Canal, Puntarenas, Santa Cruz Huatulco Mexico, Puerto Vallarta, San Diego, Seattle

Starts: Sat, Apr 25, 2026 from Miami

Ends: Sun, May 10, 2026 in Los Angeles

Cruise Ports: Miami, Cartagena, Colon, Cruising the Panama Canal, Puerto Caldera, Puerto Quetzal, Puerto Vallarta, Cabo San Lucas, Los Angeles

Starts: Thu, Apr 16, 2026 from Fort Lauderdale

Ends: Sat, May 2, 2026 in Los Angeles

Cruise Ports: Fort Lauderdale, Oranjestad, Cruising the Panama Canal, Fuerte Amador, Puntarenas, Puerto Chiapas, Huatulco, Puerto Vallarta, Los Angeles

Starts: Sat, Apr 25, 2026 from Miami

Ends: Wed, May 13, 2026 in Seattle

Cruise Ports: Miami, Cartagena, Colon, Cruising the Panama Canal, Puerto Caldera, Puerto Quetzal, Puerto Vallarta, Cabo San Lucas, Los Angeles, Seattle

Starts: Sun, Apr 5, 2026 from Los Angeles

Ends: Sun, Apr 19, 2026 in Miami

Cruise Ports: Los Angeles, Puerto Quetzal, Cruising the Panama Canal, Willemstad (Curacao), Oranjestad, Miami

Starts: Sat, Apr 11, 2026 from Miami

Ends: Wed, Apr 29, 2026 in San Francisco

Cruise Ports: Miami, Cartagena, Cruising the Panama Canal, Panama City, Puerto Caldera, Puerto Quetzal, Acapulco, Puerto Vallarta, Cabo San Lucas, San Francisco

Starts: Sat, Apr 11, 2026 from Miami

Ends: Sun, May 3, 2026 in Seattle

Cruise Ports: Miami, Cartagena, Cruising the Panama Canal, Panama City, Puerto Caldera, Puerto Quetzal, Acapulco, Puerto Vallarta, Cabo San Lucas, San Francisco, Astoria, Victoria, Seattle

Starts: Mon, Apr 13, 2026 from Fort Lauderdale

Ends: Sun, May 3, 2026 in Seattle

Cruise Ports: Fort Lauderdale, Oranjestad, Cruising the Panama Canal, Fuerte Amador, Mazatlan, Cabo San Lucas, Los Angeles, Seattle

Starts: Mon, Apr 13, 2026 from Fort Lauderdale

Ends: Thu, Apr 30, 2026 in Los Angeles

Cruise Ports: Fort Lauderdale, Georgetown , Cartagena, Colon, Cruising the Panama Canal, Puntarenas, Puerto Quetzal, Puerto Vallarta, Mazatlan, Los Angeles

Starts: Fri, Apr 10, 2026 from Fort Lauderdale

Ends: Mon, Apr 27, 2026 in San Diego

Cruise Ports: Fort Lauderdale, Cartagena, Cruising the Panama Canal, Fuerte Amador, Puerto Caldera, Acajutla, Puerto Quetzal, Puerto Chiapas, Manzanillo, Puerto Vallarta, San Diego

Starts: Sun, Apr 5, 2026 from Fort Lauderdale

Ends: Mon, Apr 20, 2026 in San Diego

Cruise Ports: Fort Lauderdale, Cartagena, Cruising the Panama Canal, Puerto Caldera, Acajutla, Puerto Quetzal, Puerto Vallarta, Cabo San Lucas, San Diego

Starts: Tue, Apr 14, 2026 from Miami

Ends: Fri, Apr 24, 2026 in Panama City

Cruise Ports: Miami, Cozumel, Costa Maya, Belize City, Roatan, Puerto Limon, Colon, Cruising the Panama Canal, Panama City

Starts: Sun, May 3, 2026 from San Diego

Ends: Sun, May 17, 2026 in Fort Lauderdale

Cruise Ports: San Diego, Manzanillo, Puerto Chiapas, Acajutla, Fuerte Amador, Cruising the Panama Canal, Cartagena, Fort Lauderdale

Starts: Fri, Apr 10, 2026 from Fort Lauderdale

Ends: Sat, May 2, 2026 in Vancouver

Cruise Ports: Fort Lauderdale, Cartagena, Cruising the Panama Canal, Fuerte Amador, Puerto Caldera, Acajutla, Puerto Quetzal, Puerto Chiapas, Manzanillo, Puerto Vallarta, San Diego, San Francisco, Vancouver

Starts: Sun, Apr 5, 2026 from Fort Lauderdale

Ends: Sat, Apr 25, 2026 in Seattle

Cruise Ports: Fort Lauderdale, Cartagena, Cruising the Panama Canal, Puerto Caldera, Acajutla, Puerto Quetzal, Puerto Vallarta, Cabo San Lucas, San Diego, Catalina Island, Vancouver, Seattle

Starts: Sun, Apr 5, 2026 from Galveston

Ends: Sun, Apr 19, 2026 in San Diego

Cruise Ports: Galveston, Cozumel, Cartagena, Cruising the Panama Canal, Puerto Vallarta, Cabo San Lucas, San Diego

Starts: Tue, Apr 14, 2026 from Miami

Ends: Thu, May 14, 2026 in Seattle

Cruise Ports: Miami, Cartagena, Colon, Cruising the Panama Canal, Puntarenas, Santa Cruz Huatulco Mexico, Puerto Vallarta, San Diego, Seattle, Ketchikan, Sitka, Glacier Bay, Juneau, Skagway, Tracy Arm Fjord, Victoria, Seattle